What to Expect at Your First Infusion Therapy

It’s completely normal to feel a mix of emotions before your first infusion treatment—curious, nervous, or maybe even both. Starting something new, especially when it involves your health, can feel overwhelming. But you’re not alone, and this step is one many people take on their treatment journey toward feeling better.

Infusion therapy delivers medication directly into your bloodstream, allowing it to work faster and more effectively than pills. Your first treatment is all about helping you feel informed, cared for, and supported.

A trained healthcare team will guide you through the process, answer your questions, and make sure you’re as comfortable as possible every step of the way.

Infusion Therapy 101

Infusion therapy is used when medication needs to be delivered directly into the body—usually through a vein or just under the skin. This method helps treatments take effect more quickly and reliably than pills.

It’s often recommended for conditions that are harder to manage with oral medications, like autoimmune disorders, chronic infections, or inflammation.

A trained infusion nurse or care provider stays with you during the infusion to monitor your comfort and check your vital signs. Many patients find this one-on-one support reassuring, especially during the first few sessions. While it might feel unfamiliar at first, infusion therapy soon becomes a routine part of care for many people—and one that can significantly improve quality of life.

What Is Infusion Therapy?

Undergoing infusion therapy involves receiving medication through a small tube placed in a vein (IV) or just beneath the skin (subcutaneous). When you receive infusion therapy, it allows the medicine to travel directly into your bloodstream or body tissues, helping it work more efficiently. This approach is especially helpful for people who can’t take medications by mouth or who need stronger, more targeted treatment.

It can be administered in different ways:

IVIG Therapy

IVIG stands for intravenous immunoglobulin. This method delivers antibodies directly into a vein using an IV line, typically at an infusion center or clinic. Each session can take a few hours, but most people only need treatments every few weeks. During the infusion, a nurse is present to help you stay comfortable and monitor your response to the therapy.

IVIG is a great option for those who prefer hands-on care or want extra support during treatment. It’s often the first step when starting IG therapy, giving your care team a clear picture of how your body responds.

SCIG Therapy

SCIG, or subcutaneous immunoglobulin, is another way to receive IG therapy—but instead of going into a vein, the medication is delivered just under the skin using a small needle. With some guidance and training, many patients are able to do SCIG at home on their own schedule.

Because SCIG uses smaller doses, it’s usually given more frequently—often once a week. This approach offers more flexibility and can feel less disruptive to daily life. It also allows patients to take more control over their treatment in a setting that’s familiar and comfortable.

Preparing for Your First Infusion Therapy Appointment

It’s natural to feel a little nervous before your first infusion appointment, but a bit of preparation can go a long way in helping you feel more at ease. Many people find that scheduling time off work, arranging for a ride, or bringing along some comfort items makes the day feel a little less overwhelming.

Sharing your health history with the care team is also an important step. Let them know about your medical history, and any current medications or past reactions to treatments—this helps them tailor your care to best meet your needs. By taking these small steps, you can ease your mind and make your visit more comfortable.

What to Bring to Your Infusion Therapy Appointment

It’s a good idea to bring a few things that help you relax or keep you entertained during the infusion session. Here are some things you might consider:

Cozy blanket to make you feel more comfortable during the session.
Book, tablet, or headphones to help pass the time with something engaging.
Water bottle and light snack in case the session runs longer than expected.
Chargers for your devices, so you don’t run out of power if you want to watch a movie or listen to music.

How to Dress Comfortably

Wearing loose-fitting, comfortable clothes is key to making your infusion experience as smooth as possible. Consider these clothing tips:

Shirts with sleeves that roll up or sleeveless tops to make vein access easier.
Light sweater to stay warm, especially if the infusion room is cool.
Warm socks for extra comfort if you’ll be seated for a longer period.
Layered clothing so you can adjust based on the room temperature.

Arranging Transportation

How you feel after your infusion therapy session can vary. Some people feel just fine and can drive themselves home, while others prefer having a friend or family member drive them for comfort and safety. Here are some tips for planning your trip home:

Arrange transportation in advance if you may be tired after the session.
Ask a friend or family member to drive you if you’re unsure how you’ll feel.
Book a ride service to help avoid the stress of coordinating last-minute transportation.

What Happens During the Infusion?

Once your IV is set up, most of the work happens quietly behind the scenes. The medication is delivered at a steady, controlled rate, and the care team closely monitors everything. Many people find themselves relaxing in a comfy chair, sometimes with a blanket, music, or even headphones.

You can choose to enjoy some quiet time or catch up on your favorite shows. The atmosphere is typically calm and soothing, which makes it easier to relax. It’s surprising how quickly the time passes once your treatment is underway.

Setting and Environment

Infusion centers are designed with comfort in mind. Soft lighting, cozy chairs, and quiet surroundings help create a soothing environment. Some centers even offer personal TVs, Wi-Fi, or music to help make the experience a little more pleasant.

At California Specialty Pharmacy (CSP), our Ambulatory Infusion Suites (AISs) provide these comforts and more—like high-speed internet, cable TV, and spacious, private infusion suites. You also have the option of receiving care in your own home if that’s a better fit for your lifestyle.

The Role of Your Care Team

Throughout your infusion, healthcare professionals are there to support you. They’ll regularly check your vital signs, monitor for any side effects, and make sure you’re comfortable. If something feels off—maybe a little dizziness or discomfort—you just have to speak up, and they’ll adjust things to help you feel better.

Questions are always welcome. The care team is there not only to deliver treatment, but also to walk you through it and help ease any concerns. At CSP’s infusion suites, our nurses and pharmacists work closely with your provider to personalize your treatment plan and support you every step of the way.

Managing Time and Duration

Infusion treatments can vary in length depending on the type of medication and how your body responds. Some may take just half an hour, while others might last a few hours. Many people bring along entertainment, like movies, music, or puzzles, to pass the time.

If you’re sitting for a while, a gentle reminder to move or take a short walk can help keep you comfortable.

CSP’s Commitment to You

At California Specialty Pharmacy, we know that starting infusion therapy can feel overwhelming, but you’re never alone.

From the first phone call to follow-up after your session, our dedicated infusion care team is here to guide you with compassion, expertise, and a personal touch. We’ll work with your provider to tailor your care and make every step as smooth and stress-free as possible. If questions come up at any point, our nurses are available 24/7 to support you.

Potential Side Effects and How to Manage Them

While receiving medication through an IV is generally safe, some side effects might occur. Most of the time, these are minor and go away on their own.

Knowing what to expect can help you feel more at ease. Being aware of potential side effects and staying in touch with your care team can make it easier to manage any bumps along the way.

Common Side Effects

Some mild side effects you might experience include:

Minor discomfort at the IV site: This is fairly common and typically goes away on its own.
Mild nausea or drowsiness: These feelings usually pass quickly and can often be managed by staying hydrated or having a light snack.
Chills: These tend to fade as your body adjusts to the medication.
Headache: If a headache lingers, it could be due to the infusion rate. Let your nurse know, and they can adjust the flow to help relieve it.

Your care team will be monitoring your progress during the infusion and will be ready to assist you with anything you need to stay comfortable.

When to Contact Your Provider

In rare cases, you may experience more serious side effects. Contact your provider if you notice:

Redness, swelling, or intense pain at the infusion site: These may require immediate attention.
High fever: This could be a sign of an infection or reaction that needs to be addressed.
Shortness of breath: This should never be ignored and needs prompt medical evaluation.
Symptoms that persist or feel more intense than expected: If anything feels off, don’t hesitate to call. Your provider might need to adjust your treatment plan.

If you’re unsure about any symptoms, it’s always best to reach out. A quick phone call can offer peace of mind or help you take the next steps to ensure your treatment stays on track.

Next Steps After Your Infusion

Once the IV is disconnected, you might feel relieved, but the infusion process doesn’t always end there. Some people experience a burst of energy, while others may feel like they need a little extra rest. Depending on the type of medication, there could be follow-up visits or calls to check on your progress. Keeping an eye on how you’re feeling after treatment can provide valuable insights into how well the therapy is working. Staying on top of any next steps recommended by your care team can help support better long-term results and bring you greater peace of mind.

Monitoring Your Health

It can be helpful to track your health in a simple notebook or on your phone. You don’t have to keep a detailed journal—just jotting down how you’re feeling each day can be enough. Small improvements, like feeling more energized or noticing fewer symptoms, can be signs that the therapy is working. But if you notice any new discomforts or ongoing side effects, it could mean that adjustments are needed.

For those receiving infusion therapy, keeping track of these changes can help your doctor fine-tune your treatment plan. Staying aware of your body’s responses can make a big difference in the success of your treatment, giving you a clearer picture of how things are going.

Scheduling Follow-up Appointments

Many treatment plans require ongoing sessions. It’s a good idea to schedule your follow-up appointments as soon as possible to keep your treatment on track. Missing a session or delaying an appointment might cause symptoms to return. In some cases, one infusion isn’t enough, and regular treatments are needed to maintain long-term improvement.

If your care team recommends routine visits, sticking to the schedule is key. It helps keep your medication levels where they need to be for the best possible results. Your provider is there to guide you every step of the way, adjusting doses or adding new strategies as needed.

Moving Forward With Confidence in Your Care

After completing an IV infusion, many patients feel a blend of relief and optimism, knowing that they’re one step closer to feeling better.

To make each visit as comfortable and stress-free as possible, remember to wear cozy clothing, bring along small comforts like a blanket or a book, and stay hydrated throughout the process. Having a caring, experienced team that’s easy to reach and ready to assist adds an extra layer of peace of mind.

By combining thoughtful self-care with open communication, you’ll be better equipped to track your progress and stay on course toward your wellness goals. At California Specialty Pharmacy, we understand that each patient’s journey is unique, and we’re here to support you every step of the way with compassionate, tailored care.

Whether you have questions, need advice, or are ready to schedule your next appointment, our team is here to help. Let us be your partner in wellness—reach out to California Specialty Pharmacy today and experience the difference of personalized care.

Frequently Asked Questions (FAQ)

What should a person expect at their first infusion?

At your first infusion, you’ll start with a check-in, possibly a few blood tests, and maybe some pre-medication. Then, the IV will be placed, and the medication will be administered while the team carefully monitors for any reactions. Afterward, there may be a short monitoring period to make sure everything is going smoothly.

What isn’t recommended before an infusion?

It’s generally best to avoid heavy meals or large amounts of caffeine before your infusion. Your healthcare provider might also recommend pausing certain medications ahead of your appointment, so be sure to check in with them about that.

How long does it take to feel results from an IV infusion?

The time it takes to feel results can vary based on the medication and your specific condition. Some people notice improvements within a few hours, while others might need more time. If you’re unsure or have any concerns, don’t hesitate to follow up with your care team about what you’re experiencing.

What’s a good outfit on infusion day?

Comfort is key. Opt for loose-fitting tops or short sleeves to make IV access easier. And since infusion rooms can sometimes be a bit cool, it’s a good idea to bring an extra layer to keep warm and cozy.

Updated on June 16, 2025. This blog is not intended to diagnose, treat, or cure any medical condition. Individual experiences with infusion therapy may vary, and healthcare decisions should always be made in consultation with a qualified healthcare provider who can offer personalized advice based on a person’s medical history and condition.

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